FLUAD TIV PRE-FILLED SYRINGES 10 PACK 2026

Fluad® Trivalent (Influenza Vaccine, Adjuvanted) 0.5 mL Single-Dose Pre-Filled Syringe – Carton of 10
2026–2027 Influenza Season

** NEEDLES NOT INCLUDED **
Age Indication: 65 years and older
Preservative Status: Preservative-free
Latex Status: No latex
CPT Code: 90653
10 Doses

Storage and Handling:
** REFRIGERATED PRODUCT **
- Store refrigerated at 2-8°C (36-46°F).
- Do not freeze. Discard if the product has been frozen.
- Protect from light.
- Do not use beyond the expiration date printed on the label

Fluad® Trivalent is an egg-based, adjuvanted, inactivated influenza vaccine indicated for intramuscular administration. It is supplied as a sterile, milky-white injectable emulsion in preservative-free, single-dose prefilled syringes.

Adjuvanted Formulation for Enhanced Immune Response

Fluad is specifically formulated with MF59C.1 (MF59®) adjuvant, a squalene-based oil-in-water emulsion designed to enhance immune response.

MF59C.1 Adjuvant Components (per 0.5 mL dose):

• Squalene – 9.75 mg

• Polysorbate 80 – 1.175 mg

• Sorbitan trioleate – 1.175 mg

• Sodium citrate dihydrate – 0.66 mg

• Citric acid monohydrate – 0.04 mg

• pH range: 6.9–7.7

The adjuvant works by stimulating a stronger immune response, particularly beneficial in older adults whose immune systems may respond less robustly to standard-dose vaccines.

Manufacturing Process

Fluad is produced using traditional egg-based technology:

• Virus propagated in embryonated hens’ eggs

• Harvested and clarified via centrifugation and filtration

• Inactivated with formaldehyde

• Purified by zonal centrifugation

• Surface antigens (hemagglutinin and neuraminidase) extracted using cetyltrimethylammonium bromide (CTAB)

• Combined with MF59C.1 adjuvant to create the final emulsion

Antigen Content

Standardized according to United States Public Health Service (USPHS) requirements.

Each 0.5 mL dose contains:

• 45 mcg total hemagglutinin (HA)

  • 15 mcg HA from each of the three recommended influenza strains

Residual Trace Components

Each dose may contain trace amounts of:

• Neomycin (≤ 0.02 mcg)

• Kanamycin (≤ 0.03 mcg)

• Hydrocortisone (≤ 0.005 ng)

• Egg protein (ovalbumin) (≤ 0.4 mcg)

• Formaldehyde (≤ 10 mcg)

• CTAB (≤ 12 mcg)

Additional Product Information

• Preservative-free

• Syringe components are not made with natural rubber latex

• Contains MF59 adjuvant

• Egg-based manufacturing

How Supplied

• 0.5 mL single-dose prefilled syringes

• Carton of 10